Kathleen Frey

Kathleen Frey

Associate Professor of Pharmaceutical Sciences, Director of Research
School of Pharmacy and Health Sciences 



  • Foundations in Pharmaceutical Sciences
  • Foundations in Biomedical Sciences
  • Integrated Pharmacotherapy
  • Principles of Drug Design
  • Toxicology of Drugs and Chemicals


  • Structure-based drug design
  • Protein/X-ray crystallography
  • Molecular modeling
  • Computational chemistry
  • Medicinal chemistry
  • Molecular pharmacology
  • Crowdsourcing research


  • BS, University of Connecticut
  • PhD, University of Connecticut

Academic Profile

Dr. Kathleen Frey joined the School of Pharmacy and Health Sciences in January 2019. Dr. Frey received a BS in Molecular and Cell Biology and a Ph.D. in Pharmaceutical Sciences (specializing in Medicinal Chemistry) from the University of Connecticut. Following graduate studies, Dr. Frey completed a postdoctoral fellowship in Pharmacology at Yale University School of Medicine. At Yale, Dr. Frey received the NIH Ruth L. Kirschstein National Research Service Award (NRSA) to develop structure-activity and structure-property relationships for non-nucleoside compounds targeting HIV. Dr. Frey has published over 30 peer-reviewed research articles on structure-based drug design for HIV, MRSA, opportunistic infections, and cancer. In addition to research, Dr. Frey was also a postdoctoral teaching scholar at Yale University and received training from Yale Center for Teaching and Learning.

In 2015, Dr. Frey accepted her first faculty position at Long Island University (LIU) Arnold and Marie Schwartz College of Pharmacy and Health Sciences. During her 3.5-year appointment, Dr. Frey taught medicinal chemistry in the professional pharmacy program and pharmacology/medicinal chemistry in the MS graduate program. Dr. Frey also conducted research at LIU and mentored several MS students conducting dissertation research. Dr. Frey received the AACP New Investigator Award in 2017 to develop computational and experimental methods to predict HIV drug resistance. She also received several internal grants at LIU and FDU to support various research projects.

Dr. Frey’s research uses computational chemistry, crystal structures, and modeling to analyze drug-target interactions. She uses these approaches to design small molecules and biologics with improved pharmacological and physiochemical properties. Dr. Frey is also interested in modeling and predicting the effects of resistance-associated mutations in drug targets.

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